ICG 001 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemICG 001
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4505/10
Quantity10 mg (also 50 mg)
Conjugate/Tag/LabelUnconjugated
StorageStore at -20°C
Molecule Name(6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
FormulaC₃₃H₃₂N₄O₄
Molecular Weight548.63
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.98

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Network-Based Integration of Multi-Omics Data Identifies the Determinants of miR-491-5p EffectsCancersAugust 5, 2021Meryet-Figuiere M, Vernon M, Andrianteranagna M, Lambert B, Brochen C, Issartel JP, Guttin A, Gauduchon P, Brotin E, Dingli F, et al.

(2) Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent MannerFrontiers in molecular neuroscienceJanuary 1, 2021Sokpor G, Kerimoglu C, Nguyen H, Pham L, Rosenbusch J, Wagener R, Nguyen HP, Fischer A, Staiger JF, Tuoc T.

(3) High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell HomeostasisCell reportsFebruary 18, 2020Aros CJ, Paul MK, Pantoja CJ, Bisht B, Meneses LK, Vijayaraj P, Sandlin JM, France B, Tse JA, Chen MW, et al.

(4) Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesisCell discoveryJanuary 1, 2018Rothberg JLM, Maganti HB, Jrade H, Porter CJ, Palidwor GA, Cafariello C, Battaion HL, Khan ST, Perkins TJ, Paulson RF, et al.

(5) Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcificationsPloS oneJanuary 1, 2018Gravesen E, Nordholm A, Mace M, Morevati M, Høgdall E, Nielsen C, Kjær A, Olgaard K, Lewin E.

(6) Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt SignalingFrontiers in immunologyJanuary 1, 2018Kling JC, Jordan MA, Pitt LA, Meiners J, Thanh-Tran T, Tran LS, Nguyen TTK, Mittal D, Villani R, Steptoe RJ, et al.

(7) ICG-001 affects DRP1 activity and ER stress correlative with its anti-proliferative effectOncotargetDecember 5, 2017Zinecker H, Ouaret D, Ebner D, Gaidt MM, Taylor S, Aulicino A, Jagielowicz M, Hornung V, Simmons A.

(8) Sam68 Allows Selective Targeting of Human Cancer Stem CellsCell chemical biologyJuly 20, 2017Benoit YD, Mitchell RR, Risueño RM, Orlando L, Tanasijevic B, Boyd AL, Aslostovar L, Salci KR, Shapovalova Z, Russell J, et al.

(9) WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in miceBlood advancesJuly 11, 2017Gatica-Andrades M, Vagenas D, Kling J, Nguyen TTK, Benham H, Thomas R, Körner H, Venkatesh B, Cohen J, Blumenthal A.

(14) WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibitedThe Journal of clinical investigationMarch 2, 2015Boulter L, Guest RV, Kendall TJ, Wilson DH, Wojtacha D, Robson AJ, Ridgway RA, Samuel K, Van Rooijen N, Barry ST, et al.

(16) A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathwayChemistry & biologyApril 24, 2014Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.

ICG 001